Interaction of Aβ42 with Membranes Triggers the Self-Assembly into Oligomers

The self-assembly of amyloid β (Aβ) proteins into oligomers is the major pathogenic event leading to Alzheimer’s disease (AD). Typical in vitro experiments require high protein concentrations, whereas the physiological concentration of Aβ is in the picomolar to low nanomolar range. This complicates...

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Detalles Bibliográficos
Autores principales: Banerjee, Siddhartha, Hashemi, Mohtadin, Zagorski, Karen, Lyubchenko, Yuri L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036922/
https://www.ncbi.nlm.nih.gov/pubmed/32046252
http://dx.doi.org/10.3390/ijms21031129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036922/
https://www.ncbi.nlm.nih.gov/pubmed/32046252
http://dx.doi.org/10.3390/ijms21031129

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