Deletion of the Nucleotide Exchange Factor Vav3 Enhances Axonal Complexity and Synapse Formation but Tampers Activity of Hippocampal Neuronal Networks In Vitro

Vav proteins activate GTPases of the RhoA subfamily that regulate the cytoskeleton and are involved in adhesion, migration, differentiation, polarity and the cell cycle. While the importance of RhoA GTPases for neuronal morphology is undisputed, their regulation is less well understood. In this pers...

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Detalles Bibliográficos
Autores principales: Wegrzyn, David, Wegrzyn, Christine, Tedford, Kerry, Fischer, Klaus-Dieter, Faissner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037001/
https://www.ncbi.nlm.nih.gov/pubmed/32013053
http://dx.doi.org/10.3390/ijms21030856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037001/
https://www.ncbi.nlm.nih.gov/pubmed/32013053
http://dx.doi.org/10.3390/ijms21030856

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