C-Terminal Domain of the Human Zinc Transporter hZnT8 Is Structurally Indistinguishable from Its Disease Risk Variant (R325W)

The human zinc transporter 8 (hZnT8) plays important roles in the storage of insulin in the secretory vesicles of pancreatic β cells. hZnT8 consists of a transmembrane domain, with its N- and C-termini protruding into the cytoplasm. Interestingly, the exchange of arginine to tryptophan at position 3...

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Detalles Bibliográficos
Autores principales: Ullah, Raheem, Shehzad, Aamir, Shah, Majid Ali, March, Matteo De, Ismat, Fouzia, Iqbal, Mazhar, Onesti, Silvia, Rahman, Moazur, McPherson, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037036/
https://www.ncbi.nlm.nih.gov/pubmed/32023808
http://dx.doi.org/10.3390/ijms21030926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037036/
https://www.ncbi.nlm.nih.gov/pubmed/32023808
http://dx.doi.org/10.3390/ijms21030926

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