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PTP4A3, A Novel Target Gene of HIF-1alpha, Participates in Benzene-Induced Cell Proliferation Inhibition and Apoptosis through PI3K/AKT Pathway

Benzene, a commonly used chemical, has been confirmed to specifically affect the hematopoietic system as well as overall human health. PTP4A3 is overexpressed in leukemia cells and is related to cell proliferation. We previously found that HIF-1alpha was involved in benzene toxicity and PTP4A3 may b...

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Detalles Bibliográficos
Autores principales: Pu, Yunqiu, Sun, Fengxia, Sun, Rongli, Man, Zhaodi, Ji, Shuangbin, Xu, Kai, Yin, Lihong, Zhang, Juan, Pu, Yuepu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037067/
https://www.ncbi.nlm.nih.gov/pubmed/32024182
http://dx.doi.org/10.3390/ijerph17030910