Cargando…

PERK-Mediated eIF2α Phosphorylation Contributes to The Protection of Dopaminergic Neurons from Chronic Heat Stress in Drosophila

Environmental high-temperature heat exposure is linked to physiological stress such as disturbed protein homeostasis caused by endoplasmic reticulum (ER) stress. Abnormal proteostasis in neuronal cells is a common pathological factor of Parkinson’s disease (PD). Chronic heat stress is thought to ind...

Descripción completa

Detalles Bibliográficos
Autores principales: Elvira, Rosalie, Cha, Sun Joo, Noh, Gyeong-Mu, Kim, Kiyoung, Han, Jaeseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037073/
https://www.ncbi.nlm.nih.gov/pubmed/32013014
http://dx.doi.org/10.3390/ijms21030845