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Celastrol Self-Stabilized Nanoparticles for Effective Treatment of Melanoma

BACKGROUND: Celastrol (CEL), a triterpene extracted from the Chinese herb tripterygium wilfordii, has been reported to have profound anticancer activities. However, poor water solubility and high side toxicities have severely restricted the clinical applications of CEL. PURPOSE: We proposed a facile...

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Detalles Bibliográficos
Autores principales: Li, Jinran, Jia, Yuxi, Zhang, Peng, Yang, Huailin, Cong, Xianling, An, Lin, Xiao, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037082/
https://www.ncbi.nlm.nih.gov/pubmed/32110017
http://dx.doi.org/10.2147/IJN.S232603