Z-Ajoene Inhibits Growth of Colon Cancer by Promotion of CK1α Dependent β-Catenin Phosphorylation

Aberrant activation of a Wnt/β-catenin pathway results in nuclear accumulation of β-catenin in colon cancer. Inhibiting β-catenin is one strategy for treating colon cancer. Here, we identified Z-ajoene, a sulfur containing compound isolated from crushed garlic, as an inhibitor of colon cancer cell g...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Hua, Jeong, Ji Hye, Kwon, Sung Won, Lee, Sang Kook, Lee, Hwa Jin, Ryu, Jae-Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037095/
https://www.ncbi.nlm.nih.gov/pubmed/32041324
http://dx.doi.org/10.3390/molecules25030703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037095/
https://www.ncbi.nlm.nih.gov/pubmed/32041324
http://dx.doi.org/10.3390/molecules25030703

Ejemplares similares