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Z-Ajoene Inhibits Growth of Colon Cancer by Promotion of CK1α Dependent β-Catenin Phosphorylation

Aberrant activation of a Wnt/β-catenin pathway results in nuclear accumulation of β-catenin in colon cancer. Inhibiting β-catenin is one strategy for treating colon cancer. Here, we identified Z-ajoene, a sulfur containing compound isolated from crushed garlic, as an inhibitor of colon cancer cell g...

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Detalles Bibliográficos
Autores principales:	Li, Hua, Jeong, Ji Hye, Kwon, Sung Won, Lee, Sang Kook, Lee, Hwa Jin, Ryu, Jae-Ha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037095/ https://www.ncbi.nlm.nih.gov/pubmed/32041324 http://dx.doi.org/10.3390/molecules25030703

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