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Gastric Corpus Mucosal Hyperplasia and Neuroendocrine Cell Hyperplasia, but not Spasmolytic Polypeptide-Expressing Metaplasia, Is Prevented by a Gastrin Receptor Antagonist in H(+)/K(+)ATPase Beta Subunit Knockout Mice

Proton pump inhibitor use is associated with an increased risk of gastric cancer, which may be mediated by hypergastrinemia. Spasmolytic polypeptide-expression metaplasia (SPEM) has been proposed as a precursor of gastric cancer. We have examined the effects of the gastrin receptor antagonist netaze...

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Detalles Bibliográficos
Autores principales: Aasarød, Kristin Matre, Waldum, Helge Lyder, Stunes, Astrid Kamilla, Sandvik, Arne Kristian, Flatberg, Arnar, Mjønes, Patricia, Syversen, Unni, Bakke, Ingunn, Fossmark, Reidar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037105/
https://www.ncbi.nlm.nih.gov/pubmed/32023822
http://dx.doi.org/10.3390/ijms21030927