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Analysis of the Effect of Increased α2,3-Sialylation on RTK Activation in MKN45 Gastric Cancer Spheroids Treated with Crizotinib

In the scenario of personalized medicine, targeted therapies are currently the focus of cancer drug development. These drugs can block the growth and spread of tumor cells by interfering with key molecules involved in malignancy, such as receptor tyrosine kinases (RTKs). MET and Recepteur d’Origine...

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Detalles Bibliográficos
Autores principales: Balmaña, Meritxell, Diniz, Francisca, Feijão, Tália, Barrias, Cristina C., Mereiter, Stefan, Reis, Celso A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037121/
https://www.ncbi.nlm.nih.gov/pubmed/31979110
http://dx.doi.org/10.3390/ijms21030722