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Structural Diversity of Sense and Antisense RNA Hexanucleotide Repeats Associated with ALS and FTLD

The hexanucleotide expansion GGGGCC located in C9orf72 gene represents the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar dementia (FTLD). Since the discovery one of the non-exclusive mechanisms of expanded hexanucleotide G(4)C(2) repeats involved in ALS an...

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Detalles Bibliográficos
Autores principales: Božič, Tim, Zalar, Matja, Rogelj, Boris, Plavec, Janez, Šket, Primož
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037139/
https://www.ncbi.nlm.nih.gov/pubmed/31991801
http://dx.doi.org/10.3390/molecules25030525