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A Comparison of Osteoblast and Osteoclast In Vitro Co-Culture Models and Their Translation for Preclinical Drug Testing Applications

As the population of western societies on average ages, the number of people affected by bone remodeling-associated diseases such as osteoporosis continues to increase. The development of new therapeutics is hampered by the high failure rates of drug candidates during clinical testing, which is in p...

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Detalles Bibliográficos
Autores principales: Sieberath, Alexander, Della Bella, Elena, Ferreira, Ana Marina, Gentile, Piergiorgio, Eglin, David, Dalgarno, Kenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037207/
https://www.ncbi.nlm.nih.gov/pubmed/32019244
http://dx.doi.org/10.3390/ijms21030912