Helicase-Like Transcription Factor HLTF and E3 Ubiquitin Ligase SHPRH Confer DNA Damage Tolerance through Direct Interactions with Proliferating Cell Nuclear Antigen (PCNA)

To prevent replication fork collapse and genome instability under replicative stress, DNA damage tolerance (DDT) mechanisms have evolved. The RAD5 homologs, HLTF (helicase-like transcription factor) and SHPRH (SNF2, histone-linker, PHD and RING finger domain-containing helicase), both ubiquitin liga...

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Detalles Bibliográficos
Autores principales: Seelinger, Mareike, Otterlei, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037221/
https://www.ncbi.nlm.nih.gov/pubmed/31973093
http://dx.doi.org/10.3390/ijms21030693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037221/
https://www.ncbi.nlm.nih.gov/pubmed/31973093
http://dx.doi.org/10.3390/ijms21030693

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