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Effect of Cholesterol on the Organic Cation Transporter OCTN1 (SLC22A4)

The effect of cholesterol was investigated on the OCTN1 transport activity measured as [(14)C]-tetraethylamonium or [(3)H]-acetylcholine uptake in proteoliposomes reconstituted with native transporter extracted from HeLa cells or the human recombinant OCTN1 over-expressed in E. coli. Removal of chol...

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Detalles Bibliográficos
Autores principales: Pochini, Lorena, Pappacoda, Gilda, Galluccio, Michele, Pastore, Francesco, Scalise, Mariafrancesca, Indiveri, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037232/
https://www.ncbi.nlm.nih.gov/pubmed/32041338
http://dx.doi.org/10.3390/ijms21031091