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Disruption of mosGILT in Anopheles gambiae impairs ovarian development and Plasmodium infection

Plasmodium infection in Anopheles is influenced by mosquito-derived factors. We previously showed that a protein in saliva from infected Anopheles, mosquito gamma-interferon–inducible lysosomal thiol reductase (mosGILT), inhibits the ability of sporozoites to traverse cells and readily establish inf...

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Detalles Bibliográficos
Autores principales: Yang, Jing, Schleicher, Tyler R., Dong, Yuemei, Park, Hyun Bong, Lan, Jiangfeng, Cresswell, Peter, Crawford, Jason, Dimopoulos, George, Fikrig, Erol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037243/
https://www.ncbi.nlm.nih.gov/pubmed/31658986
http://dx.doi.org/10.1084/jem.20190682