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Effects of interleukin-2 in immunostimulation and immunosuppression

Historically, interleukin-2 (IL-2) was first described as an immunostimulatory factor that supports the expansion of activated effector T cells. A layer of sophistication arose when regulatory CD4(+) T lymphocytes (Tregs) were shown to require IL-2 for their development, homeostasis, and immunosuppr...

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Detalles Bibliográficos
Autores principales: Pol, Jonathan G., Caudana, Pamela, Paillet, Juliette, Piaggio, Eliane, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037245/
https://www.ncbi.nlm.nih.gov/pubmed/31611250
http://dx.doi.org/10.1084/jem.20191247