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Effects of interleukin-2 in immunostimulation and immunosuppression
Historically, interleukin-2 (IL-2) was first described as an immunostimulatory factor that supports the expansion of activated effector T cells. A layer of sophistication arose when regulatory CD4(+) T lymphocytes (Tregs) were shown to require IL-2 for their development, homeostasis, and immunosuppr...
Autores principales: | Pol, Jonathan G., Caudana, Pamela, Paillet, Juliette, Piaggio, Eliane, Kroemer, Guido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037245/ https://www.ncbi.nlm.nih.gov/pubmed/31611250 http://dx.doi.org/10.1084/jem.20191247 |
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