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Targeting the interleukin-17 immune axis for cancer immunotherapy

The role of IL-17 in cancer remains controversial. Emerging evidence suggests that during early oncogenesis IL-17 supports tumor growth, whereas in established tumors IL-17 production by γδ and Th17 cells potentiates antitumor immunity. Consequently, γδ and Th17 cells are attractive targets for immu...

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Detalles Bibliográficos
Autores principales: Vitiello, Gerardo A., Miller, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037254/
https://www.ncbi.nlm.nih.gov/pubmed/31727783
http://dx.doi.org/10.1084/jem.20190456