Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2-Hydroxyphenylbenzimidazole-Based Scaffolds en Route to Donepezil-Like Compounds

An unsubstituted 2-hydroxyphenylbenzimidazole has recently been included as a scaffold in a series of hybrids (including the hit compound PZ1) based on the framework of the acetylcholinesterase (AChE) inhibitor Donepezil, which is a new promising multi-target ligand in Alzheimer’s disease (AD) treat...

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Detalles Bibliográficos
Autores principales: Piemontese, Luca, Sergio, Roberta, Rinaldo, Federica, Brunetti, Leonardo, Perna, Filippo M., Santos, M. Amélia, Capriati, Vito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037276/
https://www.ncbi.nlm.nih.gov/pubmed/32013037
http://dx.doi.org/10.3390/molecules25030574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037276/
https://www.ncbi.nlm.nih.gov/pubmed/32013037
http://dx.doi.org/10.3390/molecules25030574

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