Targeting Insulin-Like Growth Factor 1 Receptor Delays M-Phase Progression and Synergizes with Aurora B Inhibition to Suppress Cell Proliferation

The insulin-like growth factor 1 receptor (IGF1R) is a receptor-type tyrosine kinase that transduces signals related to cell proliferation, differentiation, and survival. IGF1R expression is often misregulated in tumor cells, but the relevance of this for cancer progression remains unclear. Here, we...

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Detalles Bibliográficos
Autores principales: Yamagishi, Akane, Ikeda, Yuki, Ikeuchi, Masayoshi, Yuki, Ryuzaburo, Saito, Youhei, Nakayama, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037296/
https://www.ncbi.nlm.nih.gov/pubmed/32033461
http://dx.doi.org/10.3390/ijms21031058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037296/
https://www.ncbi.nlm.nih.gov/pubmed/32033461
http://dx.doi.org/10.3390/ijms21031058

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