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Unfavorable Reduction in the Ratio of Endothelin B to A Receptors in Experimental 5/6 Nephrectomy and Adenine Models of Chronic Renal Insufficiency

Chronic renal insufficiency (CRI) is characterized by increased endothelin 1 (ET-1) synthesis. We studied rat kidney endothelin receptor A (ETA) and receptor B (ETB) expressions after 12 and 27 weeks of 5/6 nephrectomy, and after 12 weeks of 0.3% adenine diet, representing proteinuric and interstiti...

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Detalles Bibliográficos
Autores principales: Törmänen, Suvi, Lakkisto, Päivi, Eräranta, Arttu, Kööbi, Peeter, Tikkanen, Ilkka, Niemelä, Onni, Mustonen, Jukka, Pörsti, Ilkka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037353/
https://www.ncbi.nlm.nih.gov/pubmed/32023824
http://dx.doi.org/10.3390/ijms21030936