Towards an Understanding of the Mode of Action of Human Aromatase Activity for Azoles through Quantum Chemical Descriptors-Based Regression and Structure Activity Relationship Modeling Analysis

Aromatase is an enzyme member of the cytochrome P450 superfamily coded by the CYP19A1 gene. Its main action is the conversion of androgens into estrogens, transforming androstenedione into estrone and testosterone into estradiol. This enzyme is present in several tissues and it has a key role in the...

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Detalles Bibliográficos
Autores principales: Chayawan, Chayawan, Toma, Cosimo, Benfenati, Emilio, Caballero Alfonso, Ana Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037385/
https://www.ncbi.nlm.nih.gov/pubmed/32046297
http://dx.doi.org/10.3390/molecules25030739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037385/
https://www.ncbi.nlm.nih.gov/pubmed/32046297
http://dx.doi.org/10.3390/molecules25030739

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