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How p53 Molecules Solve the Target DNA Search Problem: A Review

Interactions between DNA and DNA-binding proteins play an important role in many essential cellular processes. A key function of the DNA-binding protein p53 is to search for and bind to target sites incorporated in genomic DNA, which triggers transcriptional regulation. How do p53 molecules achieve...

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Detalles Bibliográficos
Autores principales: Kamagata, Kiyoto, Itoh, Yuji, Subekti, Dwiky Rendra Graha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037437/
https://www.ncbi.nlm.nih.gov/pubmed/32033163
http://dx.doi.org/10.3390/ijms21031031