(+)-Usnic Acid Induces ROS-dependent Apoptosis via Inhibition of Mitochondria Respiratory Chain Complexes and Nrf2 Expression in Lung Squamous Cell Carcinoma

Lung squamous cell carcinoma (LUSC) has a poor prognosis, in part due to poor therapeutic response and limited therapeutic alternatives. Lichens are symbiotic organisms, producing a variety of substances with multiple biological activities. (+)-Usnic acid, an important biologically active metabolite...

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Detalles Bibliográficos
Autores principales: Qi, Wanchen, Lu, Changpeng, Huang, Huiliang, Zhang, Weinan, Song, Shaofei, Liu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037438/
https://www.ncbi.nlm.nih.gov/pubmed/32013250
http://dx.doi.org/10.3390/ijms21030876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037438/
https://www.ncbi.nlm.nih.gov/pubmed/32013250
http://dx.doi.org/10.3390/ijms21030876

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