GC-NICI-MS analysis of acetazolamide and other sulfonamide (R-SO(2)-NH(2)) drugs as pentafluorobenzyl derivatives [R-SO(2)-N(PFB)(2)] and quantification of pharmacological acetazolamide in human urine

Acetazolamide (molecular mass (MM), 222) belongs to the class of sulfonamides (R-SO(2)-NH(2)) and is one of the strongest pharmacological inhibitors of carbonic anhydrase activity. Acetazolamide is excreted unchanged in the urine. Here, we report on the development, validation and biomedical applica...

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Detalles Bibliográficos
Autores principales: Begou, Olga, Drabert, Kathrin, Theodoridis, Georgios, Tsikas, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037487/
https://www.ncbi.nlm.nih.gov/pubmed/32123599
http://dx.doi.org/10.1016/j.jpha.2019.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037487/
https://www.ncbi.nlm.nih.gov/pubmed/32123599
http://dx.doi.org/10.1016/j.jpha.2019.11.006

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