Cargando…
GC-NICI-MS analysis of acetazolamide and other sulfonamide (R-SO(2)-NH(2)) drugs as pentafluorobenzyl derivatives [R-SO(2)-N(PFB)(2)] and quantification of pharmacological acetazolamide in human urine
Acetazolamide (molecular mass (MM), 222) belongs to the class of sulfonamides (R-SO(2)-NH(2)) and is one of the strongest pharmacological inhibitors of carbonic anhydrase activity. Acetazolamide is excreted unchanged in the urine. Here, we report on the development, validation and biomedical applica...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Xi'an Jiaotong University
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037487/ https://www.ncbi.nlm.nih.gov/pubmed/32123599 http://dx.doi.org/10.1016/j.jpha.2019.11.006 |