FGF21 Protects against Aggravated Blood-Brain Barrier Disruption after Ischemic Focal Stroke in Diabetic db/db Male Mice via Cerebrovascular PPARγ Activation

Recombinant fibroblast growth factor 21 (rFGF21) has been shown to be potently beneficial for improving long-term neurological outcomes in type 2 diabetes mellitus (T2DM) stroke mice. Here, we tested the hypothesis that rFGF21 protects against poststroke blood–brain barrier (BBB) damage in T2DM mice...

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Detalles Bibliográficos
Autores principales: Jiang, Yinghua, Lin, Li, Liu, Ning, Wang, Qingzhi, Yuan, Jing, Li, Yadan, Chung, Kelly K., Guo, Shuzhen, Yu, Zhanyang, Wang, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037567/
https://www.ncbi.nlm.nih.gov/pubmed/32012810
http://dx.doi.org/10.3390/ijms21030824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037567/
https://www.ncbi.nlm.nih.gov/pubmed/32012810
http://dx.doi.org/10.3390/ijms21030824

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