An Optimised Di-Boronate-ChemMatrix Affinity Chromatography to Trap Deoxyfructosylated Peptides as Biomarkers of Glycation

We report herein a novel ChemMatrix(®) Rink resin functionalised with two phenylboronate (PhB) moieties linked on the N-α and N-ε amino functions of a lysine residue to specifically capture deoxyfructosylated peptides, compared to differently glycosylated peptides in complex mixtures. The new PhB-Ly...

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Detalles Bibliográficos
Autores principales: Kijewska, Monika, Nuti, Francesca, Wierzbicka, Magdalena, Waliczek, Mateusz, Ledwoń, Patrycja, Staśkiewicz, Agnieszka, Real-Fernandez, Feliciana, Sabatino, Giuseppina, Rovero, Paolo, Stefanowicz, Piotr, Szewczuk, Zbigniew, Papini, Anna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037614/
https://www.ncbi.nlm.nih.gov/pubmed/32050527
http://dx.doi.org/10.3390/molecules25030755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037614/
https://www.ncbi.nlm.nih.gov/pubmed/32050527
http://dx.doi.org/10.3390/molecules25030755

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