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An Optimised Di-Boronate-ChemMatrix Affinity Chromatography to Trap Deoxyfructosylated Peptides as Biomarkers of Glycation
We report herein a novel ChemMatrix(®) Rink resin functionalised with two phenylboronate (PhB) moieties linked on the N-α and N-ε amino functions of a lysine residue to specifically capture deoxyfructosylated peptides, compared to differently glycosylated peptides in complex mixtures. The new PhB-Ly...
Autores principales: | Kijewska, Monika, Nuti, Francesca, Wierzbicka, Magdalena, Waliczek, Mateusz, Ledwoń, Patrycja, Staśkiewicz, Agnieszka, Real-Fernandez, Feliciana, Sabatino, Giuseppina, Rovero, Paolo, Stefanowicz, Piotr, Szewczuk, Zbigniew, Papini, Anna Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037614/ https://www.ncbi.nlm.nih.gov/pubmed/32050527 http://dx.doi.org/10.3390/molecules25030755 |
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