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Karacoline, identified by network pharmacology, reduces degradation of the extracellular matrix in intervertebral disc degeneration via the NF-κB signaling pathway

Karacoline is a compound found in the plant Aconitum kusnezoffii Reichb. Although Aconitum kusnezoffii Reichb is widely used for the treatment of pain, very few studies have been carried out on the use of karacoline due to its potential toxicity. In this study, we selected key matrix metalloproteina...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaoli, Hong, Yingying, Zhan, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037626/
https://www.ncbi.nlm.nih.gov/pubmed/32123596
http://dx.doi.org/10.1016/j.jpha.2019.07.002