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Karacoline, identified by network pharmacology, reduces degradation of the extracellular matrix in intervertebral disc degeneration via the NF-κB signaling pathway
Karacoline is a compound found in the plant Aconitum kusnezoffii Reichb. Although Aconitum kusnezoffii Reichb is widely used for the treatment of pain, very few studies have been carried out on the use of karacoline due to its potential toxicity. In this study, we selected key matrix metalloproteina...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037626/ https://www.ncbi.nlm.nih.gov/pubmed/32123596 http://dx.doi.org/10.1016/j.jpha.2019.07.002 |