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Impact of Janus Kinase Inhibition with Tofacitinib on Fundamental Processes of Bone Healing

Both inflammatory diseases like rheumatoid arthritis (RA) and anti-inflammatory treatment of RA with glucocorticoids (GCs) or non-steroidal anti-inflammatory drugs (NSAIDs) negatively influence bone metabolism and fracture healing. Janus kinase (JAK) inhibition with tofacitinib has been demonstrated...

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Detalles Bibliográficos
Autores principales: Gaber, Timo, Brinkman, Antonia Clara Katharina, Pienczikowski, Justyna, Diesing, Karoline, Damerau, Alexandra, Pfeiffenberger, Moritz, Lang, Annemarie, Ohrndorf, Sarah, Burmester, Gerd-Rüdiger, Buttgereit, Frank, Hoff, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037633/
https://www.ncbi.nlm.nih.gov/pubmed/32013232
http://dx.doi.org/10.3390/ijms21030865