Candidate SNP Markers of Atherogenesis Significantly Shifting the Affinity of TATA-Binding Protein for Human Gene Promoters Show Stabilizing Natural Selection as a Sum of Neutral Drift Accelerating Atherogenesis and Directional Natural Selection Slowing It

(1) Background: The World Health Organization (WHO) regards atherosclerosis-related myocardial infarction and stroke as the main causes of death in humans. Susceptibility to atherogenesis-associated diseases is caused by single-nucleotide polymorphisms (SNPs). (2) Methods: Using our previously devel...

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Detalles Bibliográficos
Autores principales: Ponomarenko, Mikhail, Rasskazov, Dmitry, Chadaeva, Irina, Sharypova, Ekaterina, Drachkova, Irina, Oshchepkov, Dmitry, Ponomarenko, Petr, Savinkova, Ludmila, Oshchepkova, Evgeniya, Nazarenko, Maria, Kolchanov, Nikolay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037642/
https://www.ncbi.nlm.nih.gov/pubmed/32033288
http://dx.doi.org/10.3390/ijms21031045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037642/
https://www.ncbi.nlm.nih.gov/pubmed/32033288
http://dx.doi.org/10.3390/ijms21031045

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