Bumetanide Suppression of Angiogenesis in a Rat Model of Oxygen-Induced Retinopathy

Aquaporins (AQPs) are involved in hypoxia-induced angiogenesis and retinal damage. Bumetanide is a diuretic agent, Na(+)/K(+)/Cl(−) cotransporter (NKCC1), and AQP 1–4 inhibitor. We tested the hypothesis that early postnatal treatment with bumetanide suppresses biomarkers of angiogenesis and decrease...

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Detalles Bibliográficos
Autores principales: Guzel, Sibel, Cai, Charles L., Ahmad, Taimur, Quan, Michelle, Valencia, Gloria B., Aranda, Jacob V., Beharry, Kay D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037744/
https://www.ncbi.nlm.nih.gov/pubmed/32024231
http://dx.doi.org/10.3390/ijms21030987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037744/
https://www.ncbi.nlm.nih.gov/pubmed/32024231
http://dx.doi.org/10.3390/ijms21030987

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