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Bumetanide Suppression of Angiogenesis in a Rat Model of Oxygen-Induced Retinopathy

Aquaporins (AQPs) are involved in hypoxia-induced angiogenesis and retinal damage. Bumetanide is a diuretic agent, Na(+)/K(+)/Cl(−) cotransporter (NKCC1), and AQP 1–4 inhibitor. We tested the hypothesis that early postnatal treatment with bumetanide suppresses biomarkers of angiogenesis and decrease...

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Detalles Bibliográficos
Autores principales:	Guzel, Sibel, Cai, Charles L., Ahmad, Taimur, Quan, Michelle, Valencia, Gloria B., Aranda, Jacob V., Beharry, Kay D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037744/ https://www.ncbi.nlm.nih.gov/pubmed/32024231 http://dx.doi.org/10.3390/ijms21030987

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