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Sledgehammer to Scalpel: Broad Challenges to the Heart and Other Tissues Yield Specific Cellular Responses via Transcriptional Regulation of the ER-Stress Master Regulator ATF6α

There are more than 2000 transcription factors in eukaryotes, many of which are subject to complex mechanisms fine-tuning their activity and their transcriptional programs to meet the vast array of conditions under which cells must adapt to thrive and survive. For example, conditions that impair pro...

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Detalles Bibliográficos
Autores principales: Stauffer, Winston T., Arrieta, Adrian, Blackwood, Erik A., Glembotski, Christopher C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037772/
https://www.ncbi.nlm.nih.gov/pubmed/32046286
http://dx.doi.org/10.3390/ijms21031134