Region-Specific Sialylation Pattern of Prion Strains Provides Novel Insight into Prion Neurotropism

Mammalian prions are unconventional infectious agents that invade and replicate in an organism by recruiting a normal form of a prion protein (PrP(C)) and converting it into misfolded, disease-associated state referred to as PrP(Sc). PrP(C) is posttranslationally modified with two N-linked glycans....

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Detalles Bibliográficos
Autores principales: Makarava, Natallia, Chang, Jennifer Chen-Yu, Baskakov, Ilia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037812/
https://www.ncbi.nlm.nih.gov/pubmed/32012886
http://dx.doi.org/10.3390/ijms21030828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037812/
https://www.ncbi.nlm.nih.gov/pubmed/32012886
http://dx.doi.org/10.3390/ijms21030828

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