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Region-Specific Sialylation Pattern of Prion Strains Provides Novel Insight into Prion Neurotropism
Mammalian prions are unconventional infectious agents that invade and replicate in an organism by recruiting a normal form of a prion protein (PrP(C)) and converting it into misfolded, disease-associated state referred to as PrP(Sc). PrP(C) is posttranslationally modified with two N-linked glycans....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037812/ https://www.ncbi.nlm.nih.gov/pubmed/32012886 http://dx.doi.org/10.3390/ijms21030828 |