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Tricyclic Nucleobase Analogs and Their Ribosides as Substrates and Inhibitors of Purine-Nucleoside Phosphorylases III. Aminopurine Derivatives

Etheno-derivatives of 2-aminopurine, 2-aminopurine riboside, and 7-deazaadenosine (tubercidine) were prepared and purified using standard methods. 2-Aminopurine reacted with aqueous chloroacetaldehyde to give two products, both exhibiting substrate activity towards bacterial (E. coli) purine-nucleos...

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Detalles Bibliográficos
Autores principales: Stachelska-Wierzchowska, Alicja, Wierzchowski, Jacek, Górka, Michał, Bzowska, Agnieszka, Stolarski, Ryszard, Wielgus-Kutrowska, Beata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037862/
https://www.ncbi.nlm.nih.gov/pubmed/32033464
http://dx.doi.org/10.3390/molecules25030681