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Elucidating the H(+) Coupled Zn(2+) Transport Mechanism of ZIP4; Implications in Acrodermatitis Enteropathica

Cellular Zn(2+) homeostasis is tightly regulated and primarily mediated by designated Zn(2+) transport proteins, namely zinc transporters (ZnTs; SLC30) that shuttle Zn(2+) efflux, and ZRT-IRT-like proteins (ZIPs; SLC39) that mediate Zn(2+) influx. While the functional determinants of ZnT-mediated Zn...

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Detalles Bibliográficos
Autores principales: Hoch, Eitan, Levy, Moshe, Hershfinkel, Michal, Sekler, Israel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037870/
https://www.ncbi.nlm.nih.gov/pubmed/31979155
http://dx.doi.org/10.3390/ijms21030734