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Baicalein Alleviates Liver Oxidative Stress and Apoptosis Induced by High-Level Glucose through the Activation of the PERK/Nrf2 Signaling Pathway

Baicalein, a widely-distributed natural flavonoid, exhibits antioxidative activity in mice with type-2 diabetes. However, the underlying mechanisms remain partially elucidated. In this study, we investigated the effect of baicalein on protein kinase R-like ER kinase (PERK)/nuclear factor erythroid-2...

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Detalles Bibliográficos
Autores principales: Dong, Yuesheng, Xing, Yan, Sun, Jin, Sun, Wenlong, Xu, Yongbin, Quan, Chunshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037940/
https://www.ncbi.nlm.nih.gov/pubmed/32019168
http://dx.doi.org/10.3390/molecules25030599