NTRK Fusions in Central Nervous System Tumors: A Rare, but Worthy Target

The neurotrophic tropomyosin receptor kinase (NTRK) genes (NTRK1, NTRK2, and NTRK3) code for three transmembrane high-affinity tyrosine-kinase receptors for nerve growth factors (TRK-A, TRK-B, and TRK-C) which are mainly involved in nervous system development. Loss of function alterations in these g...

Descripción completa

Detalles Bibliográficos
Autores principales: Gambella, Alessandro, Senetta, Rebecca, Collemi, Giammarco, Vallero, Stefano Gabriele, Monticelli, Matteo, Cofano, Fabio, Zeppa, Pietro, Garbossa, Diego, Pellerino, Alessia, Rudà, Roberta, Soffietti, Riccardo, Fagioli, Franca, Papotti, Mauro, Cassoni, Paola, Bertero, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037946/
https://www.ncbi.nlm.nih.gov/pubmed/31979374
http://dx.doi.org/10.3390/ijms21030753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037946/
https://www.ncbi.nlm.nih.gov/pubmed/31979374
http://dx.doi.org/10.3390/ijms21030753

Ejemplares similares