Caspase-6 Knockout in the 5xFAD Model of Alzheimer’s Disease Reveals Favorable Outcome on Memory and Neurological Hallmarks

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and is the most common form of dementia in the elderly. Caspases, a family of cysteine proteases, are major mediators of apoptosis and inflammation. Caspase-6 is considered to be an up-stream modulator of AD pathogenesis as active...

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Detalles Bibliográficos
Autores principales: Angel, Ariel, Volkman, Rotem, Royal, Tabitha Grace, Offen, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037950/
https://www.ncbi.nlm.nih.gov/pubmed/32050445
http://dx.doi.org/10.3390/ijms21031144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037950/
https://www.ncbi.nlm.nih.gov/pubmed/32050445
http://dx.doi.org/10.3390/ijms21031144

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