The Radiolabeling of a Gly-Sar Dipeptide Derivative with Flourine-18 and Its Use as a Potential Peptide Transporter PET Imaging Agent

We have developed a novel fluorine-18 radiotracer, dipeptide 1, radiolabeled in two steps from mesylate 3. The initial radiolabeling is achieved in a short reaction time (10 min) and purified through solid-phase extraction (SPE) with modest radiochemical yields (rcy = 10 ± 2%, n = 5) in excellent ra...

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Detalles Bibliográficos
Autores principales: Molotkov, Andrei, W. Castrillon, John, Santha, Sreevidya, E. Harris, Paul, K. Leung, David, Mintz, Akiva, Carberry, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037988/
https://www.ncbi.nlm.nih.gov/pubmed/32024310
http://dx.doi.org/10.3390/molecules25030643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037988/
https://www.ncbi.nlm.nih.gov/pubmed/32024310
http://dx.doi.org/10.3390/molecules25030643

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