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Radiosynthesis of [(18)F]-Labelled Pro-Nucleotides (ProTides)

Phosphoramidate pro-nucleotides (ProTides) have revolutionized the field of anti-viral and anti-cancer nucleoside therapy, overcoming the major limitations of nucleoside therapies and achieving clinical and commercial success. Despite the translation of ProTide technology into the clinic, there rema...

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Detalles Bibliográficos
Autores principales: Cavaliere, Alessandra, Probst, Katrin C., Paisey, Stephen J., Marshall, Christopher, Dheere, Abdul K. H., Aigbirhio, Franklin, McGuigan, Christopher, Westwell, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037993/
https://www.ncbi.nlm.nih.gov/pubmed/32041321
http://dx.doi.org/10.3390/molecules25030704