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Anticancer Activities of the Quinone-Methide Triterpenes Maytenin and 22-β-hydroxymaytenin Obtained from Cultivated Maytenus ilicifolia Roots Associated with Down-Regulation of miRNA-27a and miR-20a/miR-17-5p

Natural triterpenes exhibit a wide range of biological activities. Since this group of secondary metabolites is structurally diverse, effects may vary due to distinct biochemical interactions within biological systems. In this work, we investigated the anticancer-related activities of the quinone-me...

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Detalles Bibliográficos
Autores principales: Hernandes, Camila, Miguita, Lucyene, de Sales, Romario Oliveira, Silva, Elisangela de Paula, de Mendonça, Pedro Omori Ribeiro, Lorencini da Silva, Bruna, Klingbeil, Maria de Fatima Guarizo, Mathor, Monica Beatriz, Rangel, Erika Bevilaqua, Marti, Luciana Cavalheiro, Coppede, Juliana da Silva, Nunes, Fabio Daumas, Pereira, Ana Maria Soares, Severino, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038027/
https://www.ncbi.nlm.nih.gov/pubmed/32050628
http://dx.doi.org/10.3390/molecules25030760