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Beyond Kinase Activity: ERK5 Nucleo-Cytoplasmic Shuttling as a Novel Target for Anticancer Therapy

The importance of mitogen-activated protein kinases (MAPK) in human pathology is underlined by the relevance of abnormalities of MAPK-related signaling pathways to a number of different diseases, including inflammatory disorders and cancer. One of the key events in MAPK signaling, especially with re...

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Detalles Bibliográficos
Autores principales: Tubita, Alessandro, Lombardi, Zoe, Tusa, Ignazia, Dello Sbarba, Persio, Rovida, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038028/
https://www.ncbi.nlm.nih.gov/pubmed/32023850
http://dx.doi.org/10.3390/ijms21030938