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Synthesis and Anticancer Cytotoxicity of Azaaurones Overcoming Multidrug Resistance

The resistance of tumors against anticancer drugs is a major impediment for chemotherapy. Tumors often develop multidrug resistance as a result of the cellular efflux of chemotherapeutic agents by ABC transporters such as P-glycoprotein (ABCB1/P-gp), Multidrug Resistance Protein 1 (ABCC1/MRP1), or B...

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Detalles Bibliográficos
Autores principales: Tóth, Szilárd, Szepesi, Áron, Tran-Nguyen, Viet-Khoa, Sarkadi, Balázs, Német, Katalin, Falson, Pierre, Di Pietro, Attilio, Szakács, Gergely, Boumendjel, Ahcène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038029/
https://www.ncbi.nlm.nih.gov/pubmed/32050702
http://dx.doi.org/10.3390/molecules25030764