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The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction

Triple negative breast cancer (TNBC) is the most aggressive cancer in women, and despite improved treatments, it remains a major cause of morbidity and mortality. We and others have demonstrated that different hybrid compounds targeting PARP/MAPK or other pathways to inhibit cancer progression may l...

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Detalles Bibliográficos
Autores principales: Zhang, Jiajia, Dai, Jiajia, Zheng, Qingxuan, Guo, Shuju, Yu, Yanyan, Hu, Wenpeng, Gao, Yanan, Shi, Dayong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038075/
https://www.ncbi.nlm.nih.gov/pubmed/32033205
http://dx.doi.org/10.3390/ijms21031038