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The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction
Triple negative breast cancer (TNBC) is the most aggressive cancer in women, and despite improved treatments, it remains a major cause of morbidity and mortality. We and others have demonstrated that different hybrid compounds targeting PARP/MAPK or other pathways to inhibit cancer progression may l...
Autores principales: | Zhang, Jiajia, Dai, Jiajia, Zheng, Qingxuan, Guo, Shuju, Yu, Yanyan, Hu, Wenpeng, Gao, Yanan, Shi, Dayong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038075/ https://www.ncbi.nlm.nih.gov/pubmed/32033205 http://dx.doi.org/10.3390/ijms21031038 |
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