Synthesis of 2,2,6-Trisubstituted 5-Methylidene-tetrahydropyran-4-ones with Anticancer Activity †

In our continuous search for new, relatively simple 2-alkylidene-1-oxoheterocycles as promising anticancer drug candidates, herein we report an efficient synthesis of 2,2,6-trisubstituted 5-methylidenetetrahydropyran-4-ones. These compounds were obtained in a four step reaction sequence, in which st...

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Detalles Bibliográficos
Autores principales: Bartosik, Tomasz, Kędzia, Jacek, Drogosz-Stachowicz, Joanna, Janecka, Anna, Krajewska, Urszula, Mirowski, Marek, Janecki, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038078/
https://www.ncbi.nlm.nih.gov/pubmed/32019209
http://dx.doi.org/10.3390/molecules25030611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038078/
https://www.ncbi.nlm.nih.gov/pubmed/32019209
http://dx.doi.org/10.3390/molecules25030611

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